Griezmann was a 90th-minute substitute against former team Atletico, who earned a 2-2 draw away to stuttering Barca in LaLiga on Tuesday.
A €120million signing from Atletico at the start of the season, Griezmann arrived amid much hype but the star forward has struggled at Camp Nou, where he has started on the bench against Sevilla and Athletic Bilbao in recent weeks.
Griezmann has scored eight LaLiga goals this season and 14 across all competitions for second-placed Barca, who could fall four points adrift of bitter rivals Real Madrid on Thursday.
However, Griezmann has not scored since Barca’s 1-1 draw against Napoli in the first leg of their Champions League last-16 tie prior to the coronavirus pandemic in February.
Asked about Griezmann, Simeone told Movistar: “I’m without words.”